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11/26/2021 Chris Preston
Pemphigus is a disease that causes blisters and sores on the skin or mucous membranes, like in the mouth or on the genitals.
Pemphigus could happen at any age, but it is most usually seen in people who are middle-aged or older. It tends to be a long-lasting (chronic) condition, and some types could be life-threatening without treatment. Treatment with medication generally controls it.
Pemphigus is responsible for blisters on your skin and mucous membranes. The blisters rupture easily, leaving open sores, which might ooze and become infected.
The signs and symptoms of two common types of pemphigus include:
Pemphigus is distinct from bullous pemphigoid, which is a blistering skin condition that affects senior citizens and might cause death.
When should you see a doctor?
Consult your doctor if you have blisters inside your mouth or on your skin that do not heal.
Pemphigus is an autoimmune disorder. Generally, your immune system produces antibodies to fight off harmful invaders, like viruses and bacteria. But in pemphigus, the body produces antibodies that affect cells of your skin and mucous membranes.
Pemphigus is not contagious. In most cases, it is unknown what triggers the disease.
Sometimes, pemphigus is triggered by the use of angiotensin-converting enzyme inhibitors, penicillamine, and other drugs.
Pemphigus Risk factors
Your risk of pemphigus rises if you are middle-aged or older. The condition tends to be more frequent in people of Middle Eastern or Jewish descent.
Possible complications of pemphigus are as follows:
Blisters happen with a number of more common conditions, so pemphigus, which is rare, could be difficult to diagnose. Your doctor might refer you to a specialist in skin conditions (dermatologist).
Your doctor will talk with you about your medical history and check your skin and mouth. In addition, you might undergo tests, including:
Treatment generally starts with medications that are intended to suppress blister formation. It is generally more effective when it starts as early as possible. If the use of a drug triggered your condition, stopping use of it might be enough to clear up your pemphigus.
The following prescription medications might be used alone or in combination, depending upon the type and severity of your pemphigus and whether you have other medical conditions:
Many people get better with treatment, although it might take years. Others need to take a lower dose of medication indefinitely to stop their signs and symptoms from returning. And some people require treatment in a hospital — for instance, to care for severe or infected sores.
If you or anyone you know is suffering from pemphigus, our expert providers at Specialty Care Clinics will take care of your health and help you recover.